Chemistry courses are often referred to as “weed out classes” due to the complexity of the subject. While chemistry can be daunting to comprehend, there are ways to aid students in reaching comprehension. Through multimedia such as YouTube, students are able to take in words and visuals simultaneously to enhance learning. Mayer’s research for multimedia […]
C31: Bringing the Heat: Characterizing YouTube videos about Enthalpy using Mayer’s Multimedia Principles
Many students look to YouTube videos for help with general chemistry concepts, but how well do these videos adhere to the guidelines set in place by literature that aims to increase cognitive processing without overloading it? In our study, we create a codebook based on Richard Mayer’s Multimedia Principles that we systematically apply to a […]
B43: Spin Equilibrium of Cobalt-Salen Complexes
Spin Crossover (SCO), or spin equilibrium, is a well-studied phenomenon in some metal complexes. This phenomenon occurs when changes such as heat, light, or pressure are applied to a metal complex, which the metal center responds by changing its spin state. The spin state of a metal center is the arrangement of its valence electrons, […]
B42: Remediation of “Forever Chemicals”: Adsorption of PFOA on Novel Polymer Resin
Per-and Polyfluoroalkyl Substances(PFAS) are a class of ubiquitous and highly-persistent fluoro-organic water contaminants within the environment that have been widely utilized since the 1960’s. They are utilized in numerous industrial applications as surfactants, and are found in products such as firefighting foams, makeup, nonstick cookware, waterproof fabrics, and plastics. The most common PFAS compound in […]
B41: Multimedia Learning with YouTube: Do Educational Chemistry Videos Cognitively Support Student Learning?
Especially in a post-pandemic context, the use of technology and multimedia content for teaching and learning chemistry has become increasingly prevalent. While YouTube videos may contain accurate chemistry content, the way in which information is presented affects the potential for learning. Based on evidence-based research and cognitive theory, we used Mayer’s Multimedia Principles (MMP) to […]
C40: Nanoparticle Infection of Virus Infectivity
My research area is biochemistry about cancer cell. Elevated levels of HMGA1 in cancer cells cause mis-regulation of gene expression and are associated with increased cancer cell proliferation and increased chemotherapy resistance. We used engineered viruses to deliver a decoy hyper binding site (HBS) for HMGA1 to the nucleus of cancer cells. The purpose of […]
A38: Machine Learning in Organic Chemistry: Improving the Accuracy of Elimination Reaction Predictions
In recent years, machine learning and artificial intelligence has found unique applications in a plethora of fields and industries. Specifically, in organic chemistry, machine learning algorithms have been used to predict organic synthesis strategies based on previous patented data. Although the current available programs have shown over 90% accuracy on many common industrial reactions, they […]
A37: Abiotic Proteins: ortho-Phenylene Based Foldamer Cages
Great progress has been made toward the design of secondary structure in abiotic foldamers. However, to mimic the function and behavior of proteins, well defined tertiary structure must be achieved. The self-assembly of foldamers into macrocyclic cages is a simple approach to tertiary structure. The molecular backbone chosen for our foldamer cages is the ortho-phenylenes. […]
A36: Heart Membrane Proteins’ Malfunction Leads to Long- QT Syndrome: Detergent Free Purification of KCNE1 Using Functionalized SMALPS
KCNE1 and KCNQ1 are membrane proteins located in the heart that are responsible for repolarization. Malfunction of these proteins can lead to “Long QT Syndrome”—a condition that can cause life threatening arrhythmia and sudden cardiac death. Styrene maleic acid copolymer lipid nanoparticles (SMALPS) is a membrane mimetic system that purifies a protein and allows for […]
A45: Applications of Dimethyl Carbonate for the HILIC Separation of Sugars with Charged Aerosol Detection: Greening Industrial Solvents
We have researched the use of the green solvent dimethyl carbonate (DMC) as a mobile phase modifier for different forms of chromatography, such as hydrophilic liquid interaction chromatography (HILIC), normal phase liquid chromatography, and reversed phase liquid chromatography. Our lab’s recent publication demonstrates the utility of non-toxic and biodegradable DMC as a replacement for the […]