PFAS (per/polyfluoroalkyl substances) encompass a group of roughly 12,000 man-made chemicals that are incredibly stable. Because of its widespread use and the fact that it degrades very slowly, PFAS exists practically everywhere in the environment. Concerningly, consumption of PFAS compounds due to environmental contamination has been correlated with many illnesses, prompting research into detection methods […]
A38:Using Fluorinated Tryptophan to Observe Conformational Changes in Metallo-β-Lactamase
Author(s): Ian Weber, Biochemistry Major Advisor(s): Rick Page, Department of Chemistry and Biochemistry Surendra Silwal, Department of Chemistry and Biochemistry
A39: Do Charged Residues in Grp94 Facilitate Client Binding: Insights into Chaperone Function
The Hsp90 family of chaperones functions to target misfolded proteins, prevent aggregate formation and bind to specific substrates for proper folding. Paralogs of the Hsp90 family exist in the cytoplasm (Hsp90), in the mitochondria (TRAP1) and in the endoplasmic reticulum (Grp94). The ER paralog Grp94 is of particular interest to this investigation since it is […]
A40: Gut Microbes Affect the Onset of Type 1 Diabetes
The Type 1 Diabetes research group focuses on how bacteria in the intestines affect the onset of Diabetes in non-obese Diabetic Mice(NOD). Histology is the main focus of our research which is used to see in to these organs to visualize the bacteria and what is happening within tissue cells. Many stains and antibodies are […]
A50: Investigating Methods of Controlling Weight of 4MMCA-PDA Polyimines for Electronic Applications
The Air Force has recently gained interest in using polyimines to synthesize Covalent Organic Frameworks (COFs) for electronic applications. However, COFs are difficult to process into the thin films and membranes that are needed for electronic devices due to their low solubility. 4MMCA-PDA is a novel linear polyimine with great solubility in common organic solvents […]
B35: Tunable Polymer Networks Using Chemically Fueled Dissipative Assembly and Metal-Ligand Coordination
This research is in the area of polymer chemistry, and this specific research is on the effects different metal ion ligands will cause on synthetically crafted polymerized materials. This was done through the testing of the materials through a rheological frequency sweep of the materials upon addition of the metal ligand, finding the stress modulus […]
C17: Separating Methane and Carbon Dioxide from Biogas using PDMS Membranes
Biogas is a gaseous mixture consisting primarily of methane and carbon dioxide. It is produced from the breakdown of organic waste by microorganisms. Due to the presence of methane, biogas has the potential to be converted into a value-added product. There are currently several methods of separating methane from the other components of a given […]
C18: Cracking the Code: A Retrospective, Cognitive-Focused, Multimedia Analysis of Thermodynamic YouTube Videos
Maddie Moorehead, Integrated Science Education Major Ethan Gerken, Biochemistry and Educational Leadership Major Advisor(s): Ellen Yezierski, Department of Chemistry and Biochemistry
C19: Incorporation of KCNE4 into Lipid Nanoparticles
Ilsa Miller, Biochemistry Major Advisor(s): Gary Lorigan, Department of Chemistry and Biochemistry Alison Bates, Department of Chemistry and Biochemistry
C20: Doxorubicin Chemoresistance Modulates GLUT Expression in Melanoma
Cancer continues to be a formidable threat to human health as the second leading cause of death in the United States. Many end-stage cancers frequently evolve into multidrug-resistant (MDR) forms, posing significant challenges in treatment design. To combat this, the Mancini Lab has recently devised a new mechanism of action known as Bystander-Assisted Immunotherapy (BAIT). […]