A66: A Novel Optical Method for Quantifying Neural Activity in Awake and Behaving Animals

The neurotransmitter dopamine (DA) plays a critical role in reward, motivation, and decision making. DA circuits are altered in numerous psychiatric disorders such as depression, schizophrenia, and addiction. The ability to quantify the release of DA in various neural circuits can help us better understand the underlying neural mechanisms of psychiatric disorders. A recently developed […]

A27: Development of a photocatalytic system to reduce evaporative fuel vapor emissions from automobiles

The focus of this project is on the onboard refueling vapor recovery system in automobiles and how to help resolve the issue of fuel vapors evaporating into the atmosphere. Previous studies have shown that UV-LED photocatalysis has been effective in hydrocarbon conversions. The goal by the end of this project is to develop both an […]

A15: Twist Sense Control of Internally Functionalized ortho-Phenylenes

Of particular interest are ortho-Phenylenes due to their ability to form helices, thus classifying them as foldamers. Molecules that are of this classification are of particular interest due to their potential to mimic biomolecules, thus making them available to use for practical applications. The understanding of ortho-phenylene folding is crucial in order to assemble higher […]

C22: Refining the Structural Topology of S21 Pinholin in a Lipid Bilayer Via Electron Paramagnetic Resonance

Membrane proteins are often used as targets for development of new drugs. Unfortunately, it is often difficult to determine the structures of these membrane proteins in their native environment due to hydrophobic interactions. It is estimated that 25% of all proteins are membrane proteins, yet structures have only been solved for a few hundred. Holins […]

A90: “All You Need is Love?” The Stigma Surrounding Failure to Thrive in West Africa

The immersion experience required for Global Health minors allows students to dive deeper into the world of Global Health through hands-on learning or volunteer experiences. My immersion was through the Global Health in The Gambia study abroad program, and it left me with many questions concerning maternal and pediatric health. Throughout my time in The […]

BRII-05: Retina regeneration is dependent on key neurogenic factors

Following injury, the embryonic chicken has the capacity to regenerate a neural retina via reprogramming of cells of the retinal pigment epithelium (RPE). After surgical removal of the retina, the injured RPE cells initially respond to injury by dedifferentiating to a more plastic state. However, in order to drive RPE to complete the regeneration process, […]

C89: American Opioid Crisis: An Assay of Opioid Addiction and Treatment

Opioid use disorder is a widespread issue in the United States in need of immediate attention. Over 11.5 million Americans reported having misused opioids in 2016, typically to alleviate chronic pain. By misuse or submission to said pain, people are suffering. Misuse causes addiction, and treatments are sparse, expensive, and sometimes dangerous. It is imperative […]

A13: Over Expressing and Purifying Proteins

Purity is a measurement used to describe a wide variety of things from jewelry, to drinking water. Purity is also involved in biochemistry, specifically when studying the behavior of biological mechanisms. The mechanism of interest for the Dabney-Smith lab is the twin-arginine translocation (Tat) pathway that moves proteins around the cell. To effectively study this […]

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