The purpose of this study is to find the role of mentoring relationships for STEM student success within the Bridges Scholars community at Miami University. The Bridges Scholars program is a program that is dedicated to promoting a deeper understanding of and appreciation for diversity while also providing students with resources needed to navigate throughout […]
B15: Headspace analysis of food and beverages using the tin oxide electrochemical sensor
The tin oxide electrochemical sensor is the active component in the personal breathalyzer used for ethanol detection. The sensor works by ethanol vapor reacting with oxygen species adsorbed to the SnO2 surface, then releasing trapped electrons back into the conduction band which changes the output voltage. However, to the best of our knowledge, the analytical […]
CSI-04: Comprehensive Transcriptome and Methylome of the Developing Chick Retina
The embryonic chicken (Gallus gallus) has proved an integral model organism for studying retina development. Furthermore, the embryonic chicken demonstrates the remarkable ability to regenerate retina in response to injury. Despite these important traits, a complete understanding of gene regulation during chick retinal development is lacking. Epigenetic regulation is an important class of gene regulation, […]
C12: The role of lipids in thylakoid protein insertion
Most photosynthetic proteins are synthesized in the cytoplasm of the plant cell but are used in the thylakoid membrane of the chloroplast. The cpTAT pathway is a transport pathway in the thylakoid that helps move photosynthesis-related proteins to their site of function and requires the work of three membrane proteins, Tha4, Hcf106, and cpTatC. Membranes, […]
B09: Tandem repeat’s role in bone cancer—Osteosarcoma and their detection using a novel software
My research area has been focusing on creating software for analysis of repetitive elements in the human genome and its application in cancer treatment. In particular, I have developed a program called PyMISA that can detect microsatellites from a given DNA sequence. Microsatellites are tandem repeats of length 1 – 6 base pairs (e. g., […]
BRIV-01: Establishing an Ex-Vivo System to Study Newt Retina Regeneration via RPE Reprogramming
The study of retina regeneration in animal models has been of interest due to the implication it has in developing potential treatments for retinal diseases such as macular degeneration. Newts are excellent models to study regeneration because they retain the ability to regenerate their retina into adulthood. The process by which newts regenerate their retina […]
C17: Green Tea Polyphenol and Copper Bioavailability
Understanding the three way interactions between serum albumin, copper, and epigallocatechin gallate can provide insight into how biological systems deal with excess copper, as well as the potential benefit of the major polyphenol in green tea, epigallocatechin gallate. The redox chemistry of copper plays a critical role in biological systems, as it is very useful […]
BRIII-04: Investigating the Role of Ephrin/Eph Signaling in Newt Lens Regeneration
Newts are amazing amphibians that are capable of regenerating many body parts including their limbs, brain, heart, and many eye parts. Specifically, our lab focuses on the newts’ ability to regenerate their lens. Following removal of the lens, cells from the upper portion of the iris (dorsal iris) lose their identity as iris cells and […]
C02: The Role of Macrophages in Newt Lens Regeneration
Cataract surgery has drastically improved in the past decades and improved the standard of living for millions of individuals across the globe. Despite these amazing strides, secondary cataracts occurs at a staggeringly high rate, with children being at the greatest risk of undergoing a harmful fibrotic response after the surgery and additional complications. Interestingly, organisms […]
C03: Exploring C3a Induced Retinal Pigment Epithelium (RPE) Reprogramming in the Embryonic Chick
Visual impairment due to retina diseases, such as macular degeneration, diabetic retinopathy, and retina detachment, impact over 4 million Americans each year. In the event that the retina is injured, inflammatory responses are activated, leaving a scar that hinders vision. Observations in model organisms, such as the embryonic chick, have shown that the complement component, […]
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