Humans have caused major changes to our environment, one example being pesticide pollution. Over 1 billion pounds of pesticides are used annually in the United States. Pesticides do not remain isolated in the terrestrial environment but accumulate in freshwater systems. Globally, parasite-induced diseases are on the rise and pesticide pollution may be a contributing factor. […]
A11: Identification and association of maize imprinted genes with transposable elements in maize endosperm
Genomic imprinting is believed to be an inherently epigenetic phenomenon in which differential allele expression occurs in a parent-of-origin dependent manner. In plants, imprinting is mainly observed in the endosperm, an organ specialized to supply nutrients to the developing angiosperm embryo. The major causes of genomic imprinting are changes to gene accessibility resulting from DNA […]
B38: Developing a Hyperspectral Database for Remote Sensing of Mine Waste in Tonopah, Nevada
The mine waste in and around the town of Tonopah in Nevada has been an issue for the residents for years. The issue is that without proper testing, someone may accidentally start construction on a pile of old mine waste without even realizing it. Thus creating a health hazard for both the construction workers and […]
A25: Turning a Cell Phone into a Spectrometer
Spectrometers are large and very expensive devices that are not very portable. The aim of this project is to use a cell phone and a small device that attaches onto the camera and have it output and analyze a sample similar to how spectrometers do. There are many applications for a spectrometer including but not […]
B03: Genetic Manipulation of Nerve Ensheathment in fruit flies: Impacts on Motor Behaviors
The fruit fly, Drosophila melanogaster, is a well-known genetic model organism, with over 100 years of research. Over a 10-day life cycle, an embryo hatches to give rise to a larva, which grows in size and, after a four day period of metamorphosis, a fly emerges. Each stage has distinct behaviors, which are associated with […]
BRIV-05: Induction of Retina Regeneration by Interleukin-6
Millions of people throughout the world suffer from visual impairment due to retinal degenerative diseases such as age-related macular degeneration and retinitis pigmentosa. These afflictions can lead to severe retinal damage which does not heal spontaneously. The embryonic chick has been used as a model organism to study retina regeneration in the hopes to find […]
A24: Developing Non-invasive Real-time Metabolic Monitoring Using Spectral Phasors on Autofluorescence
Spectral phasor analysis of NADH autofluorescence has been shown to be an effective approach to measuring cellular metabolism. Extending this technique to tissue samples offers a novel method for non-invasive, real-time monitoring of healthy and diseased states of tissue. However, complex light interactions within tissue offer a significant barrier to autofluorescence measurements. To characterize the […]
B06: Harnessing CRISPR-Cas9 to Reprogram Cell Fate
Destruction of the neural retina in mammals currently leads to irreversible blindness. Unlike humans, newts possess the ability to regenerate a functional neural retina from their retinal pigmented epithelium (RPE), a cell type that lies behind the neural retina. We will develop a method to individually regulate genes by activating and repressing specifically targeted genes. […]
C19: Engineering an Oncolytic Adenovirus to Specifically Target Pancreatic Cancer
Pancreatic cancer remains a disease with an incredibly high mortality rate since it is virtually undetectable in its early stages and is difficult to treat with current therapies in later stages. The gene high mobility group AT-hook 1 (HMGA1) is upregulated in this type of cancer, which increases the resistance to chemotherapy and increases tumor […]
B30: The H2O2 reduction in Ca2+, NaHCO3 environment and the measurement of CaCO3: solid formed on the surface disk of nano-electrode
The water reduction experiment was done before with Ca2+ and NaHCO3 and found the current would jump up when the potential approached to a negative value around -1V. It may be caused by the H2 bubble formed or CaCO3 solid formed on the surface of nanoelectrode to block the current. Thus, the aim of this […]
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