My research area has been focusing on creating software for analysis of repetitive elements in the human genome and its application in cancer treatment. In particular, I have developed a program called PyMISA that can detect microsatellites from a given DNA sequence. Microsatellites are tandem repeats of length 1 – 6 base pairs (e. g., […]
BRIV-01: Establishing an Ex-Vivo System to Study Newt Retina Regeneration via RPE Reprogramming
The study of retina regeneration in animal models has been of interest due to the implication it has in developing potential treatments for retinal diseases such as macular degeneration. Newts are excellent models to study regeneration because they retain the ability to regenerate their retina into adulthood. The process by which newts regenerate their retina […]
C17: Green Tea Polyphenol and Copper Bioavailability
Understanding the three way interactions between serum albumin, copper, and epigallocatechin gallate can provide insight into how biological systems deal with excess copper, as well as the potential benefit of the major polyphenol in green tea, epigallocatechin gallate. The redox chemistry of copper plays a critical role in biological systems, as it is very useful […]
BRII-06: National Identity in Education: A Comparative Analysis of Italy and Northern Ireland
From the United Kingdom’s recent European Union withdrawal to escalating far-right populism, European states are actively reworking to differentiate their national narratives. Not surprisingly, education has been a useful tool for indoctrinating a collective national identity since the beginning of the nation-state. This paper concentrates on the complexities behind national identity within education, the similarities […]
A53: Alleviating Menstrual Discomfort in Rural India: The Comfort Care Kit
Menstrual health is a longstanding taboo topic in many countries. History of exclusion, rare preemptive treatment, and discomfort is the reality for women across the world. In India, this lack of treatment and feelings are not uncommon. Four aspects of menstruation are present; Treatment is sought only after a major issue and remains unresolved for […]
A61: Let’s Talk Period in Global Health: Addressing Cultural Taboos and Societal Perceptions about Women in Rural Karnataka
The primary focus is to open a space where menstruation can be considered a healthy and normal process among all women. Menstruation integrates countless myths and taboos across the world; with the number of myths increasing daily it has a negative implication of adolescent health. Proper menstrual health is a global health concern and getting […]
BRIII-04: Investigating the Role of Ephrin/Eph Signaling in Newt Lens Regeneration
Newts are amazing amphibians that are capable of regenerating many body parts including their limbs, brain, heart, and many eye parts. Specifically, our lab focuses on the newts’ ability to regenerate their lens. Following removal of the lens, cells from the upper portion of the iris (dorsal iris) lose their identity as iris cells and […]
C02: The Role of Macrophages in Newt Lens Regeneration
Cataract surgery has drastically improved in the past decades and improved the standard of living for millions of individuals across the globe. Despite these amazing strides, secondary cataracts occurs at a staggeringly high rate, with children being at the greatest risk of undergoing a harmful fibrotic response after the surgery and additional complications. Interestingly, organisms […]
C03: Exploring C3a Induced Retinal Pigment Epithelium (RPE) Reprogramming in the Embryonic Chick
Visual impairment due to retina diseases, such as macular degeneration, diabetic retinopathy, and retina detachment, impact over 4 million Americans each year. In the event that the retina is injured, inflammatory responses are activated, leaving a scar that hinders vision. Observations in model organisms, such as the embryonic chick, have shown that the complement component, […]
A66: A Novel Optical Method for Quantifying Neural Activity in Awake and Behaving Animals
The neurotransmitter dopamine (DA) plays a critical role in reward, motivation, and decision making. DA circuits are altered in numerous psychiatric disorders such as depression, schizophrenia, and addiction. The ability to quantify the release of DA in various neural circuits can help us better understand the underlying neural mechanisms of psychiatric disorders. A recently developed […]
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