Within the field of biochemistry, chaperone and co-chaperone proteins are of important significance due to their vital role in assisting protein folding. ERdj6 is an Hsp40 co-chaperone that works with Hsp70 to facilitate client binding and folding. ERdj6 was grown and purified in E. Coli, with wild-type and mutant protein samples grown. Within Hsp40 proteins […]
A43: Vulnerability and Agency: A Study of the Refugee and Migrant Women of Calais from 2014-2016
The “Jungle of Calais”, a sprawling migrant and refugee camp that existed most prominently from 2014-2016, served as a living representation of the difficulty European states had navigating the influx of 5.6 million migrants and refugees seeking asylum during the European Migrant Crisis. By the end of 2016, 10,000 people inhabited the Jungle of Calais. […]
A44: The Effects of Psilocybin on Decision Making and Motivation
There has been a resurgence in research regarding the therapeutic potential of hallucinogenic psilocybin. Although this research is promising, much is unknown about how psilocybin impacts behavior from a pharmacological perspective. It is established that psilocybin is a serotonergic agonist with affinities for several different serotonin receptors; binding affinity data indicate that psilocybin has a […]
A45: Evaluation of the Safety of Various E. Coli Derived Tryptamine Compounds
Clinical trials on the use of psilocybin (PSL) to treat depression are promising, but still in preliminary stages. Additionally, they are confounded by the presence of hallucinations, which may not be necessary for its clinical effectiveness but create challenges when designing experiments. Results from our lab have also indicated potential antidepressant efficacy for a number […]
A46: Healthy Eating Index Scores in Older Adults during a 6-month Weight Loss Intervention
Background: Little research has been done to understand the diet quality of older adults and even less is known about the impact of weight-loss interventions on diet quality in older adults.Methods: A randomized sample of 38 overweight, older adults in a diet or non-diet intervention group completed a 6-month weight loss intervention. Healthy Eating Index […]
A47: Critically Evaluating Apps Used to Teach Phonics to Young Children
As we learn more about child language development, we are curious as to how each individual child best develops the necessary skills to succeed. In today’s world, we are constantly being bombarded with technology; on average, people use apps on their devices between 194-223 days a year (Pontin et al., 2021). With the increasingly large […]
A48: Pseudoscience and Ghost Tours in Mansfield, OH
Frank Hanger, a well-known ghost at the Ohio State Reformatory, gave me permission to conduct my research in June 2021. His response to my question about my USS project was through the blink of a flashlight, “translated” by a volunteer at the Ohio State Reformatory. This experience was reflective of other paranormal investigation techniques I […]
A49: The War on “Science” in the #ClimateChange Echo Chamber
Climate change discourses on social media are often hardly about climate change at all. Outside of information posted by scientific institutions like NASA or climate activists such as Greta Thunberg, the discussions about climate change appear far removed from debates on actual “science.” One blog that appears to focus on information about climate science posts […]
A50: Planning for Equity and Affordability Amid Transit-Oriented Development
This project examined the impact of transit-oriented development (TOD) on affordability in adjacent neighborhoods. Despite its many environmental and economic benefits, TOD often contributes to gentrification in urban areas, which can result in decreased affordability in the community and displacement of original residents. This project examined four case study neighborhoods in the Washington, D.C. metropolitan […]
A52: Effects of Early Life Physical Inactivity Using the Novel Model of Small Mouse Cage on Growth and Health in Adulthood
Physical activity (PA) is a vital behavior to maximize health and wellness. Less is understood regarding the impact of physical inactivity on children, specifically during key stages of skeletal muscle development. We previously demonstrated that 2 weeks of extreme muscle tissue during 4-6 weeks of age causes a reduction in grip strength in adults (5 […]