Rotavirus (RV) is a pathogen that causes gastroenteritis in humans and animals. Although there are A-G types of rotavirus, type A (RVA) is the most commonly studied because it is the leading cause of death in children under 5 years averaged with 200,000 deaths a year. Understanding the infection biology of group B rotavirus (RVB) […]
A31: Micro Parties with Phage Astartes: A New Bacteriophage from Ruder Preserve
The Howard Hughes Medical Institute’s SEA-PHAGES program provides opportunities for college students in about 150 institutions around the world to participate in discovery-based science by isolating and characterizing new bacteriophages from the environment. Bacteriophages (phages) are highly abundant viruses that infect bacteria and play significant roles in ecology and health, with recent successes in helping […]
C40: Nanoparticle Infection of Virus Infectivity
My research area is biochemistry about cancer cell. Elevated levels of HMGA1 in cancer cells cause mis-regulation of gene expression and are associated with increased cancer cell proliferation and increased chemotherapy resistance. We used engineered viruses to deliver a decoy hyper binding site (HBS) for HMGA1 to the nucleus of cancer cells. The purpose of […]