Through mutations and horizontal transfer, bacteria has been able to acquire different forms of antibiotic resistance. In particular, bacteria that produce β-lactamases as a result of mutated or acquired genes have the ability to break down the β-lactam ring structure in many common classes of antibiotics (penicillins, carbapenems, monobactams, and cephalosporins). Metallo-β-lactamases, enzymes that confer […]