The Hsp90 family of chaperones functions to target misfolded proteins, prevent aggregate formation and bind to specific substrates for proper folding. Paralogs of the Hsp90 family exist in the cytoplasm (Hsp90), in the mitochondria (TRAP1) and in the endoplasmic reticulum (Grp94). The ER paralog Grp94 is of particular interest to this investigation since it is […]
A43: Striatal Cholinergic Interneurons Influence Ethanol Drinking
Heavy alcohol use and binge drinking are important contributors to alcohol use disorder (AUD). The endogenous opioid system has been implicated in alcohol consumption and preference in both humans and animals. The mu opioid receptor (MOR) is expressed on multiple cells in the striatum, however little is known about the contributions of specific MOR populations […]
A49: Impact of Climate Change on Sus scrofa Distribution in North America
The connection between race and type of delivery has been an increasing public health concern for many years. It is significant because cesarean deliveries are more risky for both mother and baby. This research project analyzes the association between race and type of delivery among women in the United States. We used data (2017-2018 cycle) […]
A50: Investigating Methods of Controlling Weight of 4MMCA-PDA Polyimines for Electronic Applications
The Air Force has recently gained interest in using polyimines to synthesize Covalent Organic Frameworks (COFs) for electronic applications. However, COFs are difficult to process into the thin films and membranes that are needed for electronic devices due to their low solubility. 4MMCA-PDA is a novel linear polyimine with great solubility in common organic solvents […]
A53: Characterization of the Fourth Alpha Isoform of the Na,K-ATPase in Human Brain Tissue
The Na+/K+ ATPase is an electrogenic transmembrane ion transport protein that localizes to the plasma membrane in mammals. Its primary function is to maintain the sodium ion and potassium ion electrochemical gradients across the plasma membrane; it does so by utilizing ATP molecules as an energy source. Three major polypeptides make up the Na+/K+ ATPase—the […]
A51: Syphilis on the rise: prevalence, incidence, and vertical transmission in Peru and USA
Syphilis has been on the rise over the past decade around the world, with a 219% increase in the United States.6 This has been a significant concern, particularly for mothers, given that syphilis has the potential for vertical transmission from mother to fetus.2 Once vertically transmitted, side effects include stillbirth, neonatal death, premature delivery, or […]
A52: Effects of Arbuscular Mycorrhizal Fungi and Rhizobia Bacteria on Reproduction in Chamaecrista fasciculata
Prairies once constituted a large portion of midwestern ecosystems and the North American landscape in general, until European settlers altered the land use. Now, 99% of prairies east of the Missouri River have been lost. Prairie restorations often produce more complex ecosystems than the sites they began on, but they lack the plant diversity found […]
A54: Differences in DNA-Methylation Patterns of the ATP1A4 Gene Between Spermatogenic and Somatic Cell Lines
The Na+/K+-ATPase alpha4 (ATP1A4 gene) ion transporter is an essential protein for sperm cells, as it helps establish an ion gradient used by secondary Na/H exchangers, ultimately directing the intracellular pH of sperm. As this gene has been found significant in spermatogenic cells, previous literature points to differences in DNA methylation patterns of the ATP1A4 […]
A57: A Comparative Transcriptomic Analysis of 21EM15 Cells with Native Lens Epithelia and Fiber Cells
The lens is a transparent organ at the front of the eye that transmits and focuses light onto the retina. The proliferative abilities of the cellular components of the lens contribute to its ability to grow throughout an individual’s life. The lens consists of two main cell types: epithelial cells and fiber cells. There is […]
A58: Alaskan Bee Populations
Pollinators are an increasingly important area of study, especially in agriculture where they are vital for crop production. Pollinator surveys are a practical way to assess the health and diversity of a population and its stability for future generations. In many places, studies like this are already commonplace and well-researched. However, in places like Alaska, […]