We have researched the use of the green solvent dimethyl carbonate (DMC) as a mobile phase modifier for different forms of chromatography, such as hydrophilic liquid interaction chromatography (HILIC), normal phase liquid chromatography, and reversed phase liquid chromatography. Our lab’s recent publication demonstrates the utility of non-toxic and biodegradable DMC as a replacement for the […]
C17: Normal Phase and Reversed Phase Liquid Chromatography Using Dimethylcarbonate as the Mobile Phase Modifier Solvent
A growing focus in the field of green analytical chemistry has been the development of greener solvents. Thus, the idea of replacing toxic solvents used in high performance liquid chromatography (HPLC) has become a priority. Previous work has shown that dimethyl carbonate (DMC) is a useful replacement for acetonitrile in hydrophilic interaction liquid chromatography (HILIC). […]