Carbodiimide-driven anhydride formation from carboxylic acids is useful in a variety of non-equilibrium systems. While there are multiple strategies to control deactivation (anhydride hydrolysis) rates, control over activation (anhydride formation) rates is limited. We show that pyridine derivatives reversibly form adducts with 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide methiodide in water. These adducts are unreactive with carboxylic acids and thus […]
A21: Condensed Tannin Characterization by Modified Saw Tooth HPLC System
Author(s): Kathyrn Williams, Chemistry Major Advisor(s): Ann Hagerman, Department of Chemistry and Biochemistry
A27: Investigating the Infection Biology of Group B Rotavirus
Rotavirus (RV) is a pathogen that causes gastroenteritis in humans and animals. Although there are A-G types of rotavirus, type A (RVA) is the most commonly studied because it is the leading cause of death in children under 5 years averaged with 200,000 deaths a year. Understanding the infection biology of group B rotavirus (RVB) […]
A33: Foldamer Synthesis and Potential Applications
The general area our lab researches is organic chemistry. The purpose of our research is to create a foldamer capable of switching on in the presence of a chemical fuel. A foldamer is a discrete chain molecule that folds into a conformationally ordered state in solution. They are artificial molecules that mimic the ability of […]
A37: What’s in the Water? Developing a Selective PFAS Sensing Platform Using Novel ssDNA Aptazymes
PFAS (per/polyfluoroalkyl substances) encompass a group of roughly 12,000 man-made chemicals that are incredibly stable. Because of its widespread use and the fact that it degrades very slowly, PFAS exists practically everywhere in the environment. Concerningly, consumption of PFAS compounds due to environmental contamination has been correlated with many illnesses, prompting research into detection methods […]
A50: Investigating Methods of Controlling Weight of 4MMCA-PDA Polyimines for Electronic Applications
The Air Force has recently gained interest in using polyimines to synthesize Covalent Organic Frameworks (COFs) for electronic applications. However, COFs are difficult to process into the thin films and membranes that are needed for electronic devices due to their low solubility. 4MMCA-PDA is a novel linear polyimine with great solubility in common organic solvents […]
B35: Tunable Polymer Networks Using Chemically Fueled Dissipative Assembly and Metal-Ligand Coordination
This research is in the area of polymer chemistry, and this specific research is on the effects different metal ion ligands will cause on synthetically crafted polymerized materials. This was done through the testing of the materials through a rheological frequency sweep of the materials upon addition of the metal ligand, finding the stress modulus […]
C26: Best of the Best? How Most Viewed Enthalpy Chemistry Education Videos Stand up to Mayer’s Multimedia Learning Principles
This presentation focuses on identifying trends related to diversity, equity, and inclusion in academic writing on topics in music. Looking at these trends creates a greater understanding of how musicological societies and their associated journals, specifically the Journal of the American Musicological Society (JAMS) and the Journal of the Society for American Music (JSAM), interact […]
C34: Development of a Bacteria Biosensor for Herbicide Detection
Escherichia coli (E. coli) has been used as a biosensor for detection of a wide range of analytes such as TNT, insecticides or lead. Glyphosate is a widely-used herbicide in US agriculture that can pose harms to marine life, mammals and endangered species. Due to the structural similarities between glycine, an amino acid that has […]
C41: Thermal Stability of Yeast Alcohol Dehydrogenase in the Undergraduate Teaching Lab
The enzyme yeast alcohol dehydrogenase (YADH) is used in the undergraduate biochemistry lab class at Miami University to teach students essential biochemical methods and concepts. Specifically, the students compare the wild type enzyme to overexpressed His-tagged YADH. An experiment was designed for students to monitor protein stability over time using recently “upcycled” HP 8453 UV/Vis […]