This project falls under the research topics of protein structure, dynamics, function, and biophysical chemistry.The main focus of this project is to elucidate the secondary structure of a viral bacteriophage protein from the ΦKT podoviridae that infects E.coli bacteria. The protein of interest is the gp28 endolysin protein that most likely functions to break the […]
C24: Purification and Characterization of Human KCNQ1 (100-370), a Voltage Gated Potassium Ion Channel, in Lipid Bilayers Using Solid-State NMR; Human KCNQ1 (100-370)/KCNE1 Interaction Studies Using EPR
KCNQ1 (Q1 or Kv7.1 or KvLQT1) is a membrane bound voltage gated potassium channel that is modulated by another membrane protein KCNE1 (E1). Q1 is an integral protein involved in the cardiac repolarization phase of a heartbeat following the action potential. E1 is an accessory protein that complexes with Q1 to form a 4:2 Q1:E1 […]