DCS measures light intensity fluctuations of blood flow in deep tissue as time passes between detection of each photon. Using fiber optic probes, a DCS system directs light from a laser into a tissue sample, and then into a single photon detector. When the laser hits the sample through the multi modal probe, light is […]
B19: Examining Sex Differences in Ethanol Consumption Using the Four Core Genotypes Model
Previous research has shown that female rodents have higher rates of alcohol consumption than males, but the mechanisms underlying these behavioral differences have yet to be uncovered. Here, we used the Four Core Genotype mouse model along with Intermittent Access to evaluate the effects of gonadal hormones and sex chromosomes on drinking habits. Four Core […]
A63: Non-invasive and Non-destructive Sensing for Food Quality Control Using Optical Spectroscopy
Developing nondestructive methods to evaluate food quality of agricultural materials play an important role in food safety and quality control. Being able to quickly, yet effectively assess the ripeness or condition of foods such as fruits and vegetables can help to prevent hazardous or over ripened food products from entering consumers’ shopping carts. One of […]
A13-T: Using Diffuse Reflectance Spectroscopy (DRS) to Observe the Development of Pressure Injuries
Pressure Injuries are a major concern in medicine, yet their origins and pathologies are relatively unknown. The origins of these issues are continually studied but they are relatively unknown and cost the healthcare industry millions of dollars each year. Low-cost alternatives include optical techniques, which have previously been used to study tissue sample compositions and […]
B45-P: Development of a Portable Diffuse Correlation Spectroscopy System for Tissue Flowmetry
Diffuse Correlation Spectroscopy (DCS) is a technique used in biomedical optics that uses collimated light — a laser — to explore flow rates in the body. Significant applications for DCS include analysis of rates associated with blood flow and cerebral spinal fluid, though DCS can be applied in many situations. DCS is an attractive technology […]
A43-P: A System for Fluorescence-based Metabolic Sensing for Cells embedded in Collagen
Thomas Finn, Nick Mayer, and Dr. Urayama, with the help of Taylor Phillips, Bibek Dhakal, and the Department of Physics, elaborate on the next steps of metabolic sensing using autofluorescence in Saccharomyces cerevisiae, baker’s yeast. A turbid mixture of baker’s yeast cells in Phosphate-Buffered Saline was excited using a nitrogen-gas discharge laser with a 1-nm […]
A24: Developing Non-invasive Real-time Metabolic Monitoring Using Spectral Phasors on Autofluorescence
Spectral phasor analysis of NADH autofluorescence has been shown to be an effective approach to measuring cellular metabolism. Extending this technique to tissue samples offers a novel method for non-invasive, real-time monitoring of healthy and diseased states of tissue. However, complex light interactions within tissue offer a significant barrier to autofluorescence measurements. To characterize the […]
A23: Biomedical Applications of Sensing Multi-State Metabolic Behavior from Cellular Autofluorescence
One way to detect metabolic change in cells is through a method called laser-induced fluorescence spectroscopy which involves exciting the cellular sample using a laser and measuring the spectrum of its autofluorescence emission. In order to detect metabolic change, we monitor autofluorescence emission in real time, and through past studies we are able to quantify […]
B47: Physics Education: Introductory Student Self-Efficacy and Problem-Solving Approaches
Physics education research focuses on how to improve the effectiveness of student learning and curriculum development. This area of physics education specifically focuses on students in introductory physics courses and how their self-efficacy and problem-solving methods change over the course of a semester. By tracking the improvement or deterioration of a student’s abilities, the Miami […]
You must be logged in to post a comment.