A06: Effect of early life physical inactivity level on growth and muscle health during early postnatal development

Background: Physical inactivity (PIA) can negatively impact health and maybe development.  Less is understood regarding the impact of physical inactivity during key stages of skeletal muscle development on adult health. Purpose: We propose that exposure to PIA early in life will impair growth rate, muscular function and tissue composition in adulthood. Methods: We exposed postnatal […]

B33: Impact of One-Week Motorized Scooter Use on Glucose Control

BACKGROUND: Assistive transportation devices are becoming popular. The effect of these devices, such as motorized scooters, on health is unclear. PURPOSE: We examined glucose control in healthy adults before and after riding a motorized scooter for one week. METHODS: In this three-week study, participants (n= 8; age: 22.5±3.8 y (mean±SD); BMI: 26.9±9.9 kg/m²) performed their […]

B40: Impact of short-term assistive transportation use on Hemodynamics and vascular function in adults

Background Physical inactivity is associated with an increased risk for cardiometabolic disease. Using an assistive transportation device may reduced physical activity that impairs health. Purpose We investigated the effect of short-term access to an assistive transportation device (electric scooter) as a proxy for reduced physical activity on hemodynamics and vascular function in adults. We hypothesized […]

C35: Early postnatal voluntary wheel running impacts on growth rate, grip strength, muscle mass, and body composition

Introduction and Purpose Physical activity (PA) is a vital behavior to maximize health. Less is understood regarding the impact of physical activity opportunities in key stages of skeletal muscle development, such as the time frame between weaning and sexual maturation. We propose that, in opposition to the negative effects of disuse, exposure to voluntary wheel […]

A52: Effects of Early Life Physical Inactivity Using the Novel Model of Small Mouse Cage on Growth and Health in Adulthood

Physical activity (PA) is a vital behavior to maximize health and wellness. Less is understood regarding the impact of physical inactivity on children, specifically during key stages of skeletal muscle development. We previously demonstrated that 2 weeks of extreme muscle tissue during 4-6 weeks of age causes a reduction in grip strength in adults (5 […]

C56: Long Term Effect of Physical Inactivity on Macrophage Inflammation and Extracellular Matrix in Postnatal Mice

Background: Physical inactivity has many detrimental effects on health, yet the impact of physical inactivity in early life on muscle health in adulthood remains unknown. Early postnatal malnutrition has prolonged effects into adulthood and we propose that early postnatal physical inactivity would have similar effects Hypothesis: When placed under physical inactivity conditions, significant differences will […]

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