Our lab uses the Acheta domesticus cricket to study the Fragile X mental retardation (FMR1) gene. FMR1 is associated with Fragile X syndrome (FXS), a genetic disorder, which is the single leading cause of intellectual disability and the primary cause of Autism spectrum disorder (ASD). FXS often presents with developmental delays, learning disabilities, and social […]
C19: Regulation of Lysozyme Expression and Activity by the Fragile X Mental Retardation Gene
Fragile X Syndrome (FXS), a genetic disorder involving mutation of the Fragile X mental retardation (FMR1) gene, accounts for up to 50% of Autism Spectrum Disorder (ASD) cases. While many studies have examined cognitive deficits associated with FXS, effects on the immune system have not been well-researched. ASD patients are reported to have increased blood […]