Regeneration is an extraordinary process shared across a diverse range of organisms. However, for most organisms, including humans, the range of regenerative capacity is lost after embryonic development and declines as development progresses. The mechanisms responsible behind the decline in regenerative capacity still need to be better understood. Some vertebrates, such as newts, have remarkable […]
C19: Establishing Genome Editing Tools for Studying Lens Regeneration
Regeneration has been a topic of research since the 18th century. Researchers have sought to understand and manipulate the mechanisms of regeneration, in the hopes of, applying these to humans. Human regenerative abilities are vastly different from those of salamanders. Interestingly, salamanders such as the newt possess high regenerative abilities and will, therefore, be used […]
C20: Insights Into Cell-cycle Dynamics and Regulation During Lens Regeneration in Pleurodeles waltl
Regeneration, or the ability to recover the architecture and function of the injured tissue, is a property shared by many organisms in the animal kingdom. However, for most organisms, including humans, regeneration capacity is lost or becomes limited after embryonic development, and declines with age. The mechanisms responsible behind the decline of regeneration capacity with […]
C13-T: In Vivo Imaging of Newt Lens Regeneration: Novel Insights Into the Regeneration Process
Newts are an exquisite salamander with unique capability of regenerating most of its tissues and organ. Its lens among all other body parts are the most significant, given when original lens is damaged or lost, a new fully functional lens would be regenerated regardless of age or repeated damage. Our research group has been focused […]