Our lab uses the Acheta domesticus cricket to study the Fragile X mental retardation (FMR1) gene. FMR1 is associated with Fragile X syndrome (FXS), a genetic disorder, which is the single leading cause of intellectual disability and the primary cause of Autism spectrum disorder (ASD). FXS often presents with developmental delays, learning disabilities, and social […]
C75: Why Does Reducing fmr1 Expression Cause Males, but Not Females, to Succumb to an Immune Challenge?
Dysfunction of the Fragile X mental retardation (FMR1) gene results in the genetic disorder Fragile X syndrome (FXS), a primary cause of Autism Spectrum Disorder (ASD). FXS patients exhibit developmental delays and learning disabilities. Although researchers have also reported immune dysregulation in FXS patients, and the fruit fly Drosophila, the role FMR1 plays in immune […]