B29: Examining Sex Chromosome and Gonadal Hormone Influences on Fear Learning in Mice

There are known disparities in susceptibility to psychiatric and stress-related disorders between sexes. Post-traumatic stress disorder (PTSD) is one such case. We used stress-enhanced fear learning (SEFL), a validated animal model for PTSD. However, it is unknown if sex differences stem from gonadal (Sry + vs. Sry -) or chromosomal (XX vs. XY) differences. The […]

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