Posttraumatic stress disorder (PTSD) is a debilitating condition that occurs in a subset of individuals who experience one or more traumatic events. It is marked by recurrent memories of the traumatic event, heightened anxiety states, altered mood, and avoidance behaviors. Importantly, adverse early childhood experiences yield increased vulnerability to the development of PTSD later in […]
C38-P: Role of β-Adrenergic Signaling in Infant Stress-Enhanced Fear Learning
Early life stress (ELS) produces an increased vulnerability for post-traumatic stress disorder (PTSD). One of the hallmark characteristics of PTSD is an increase in fear responding over time (Elharrar et al., 2013). Using a well-established rodent model developed in our lab between early life adversity and the development of PTSD-like phenotype, which we call stress-enhanced […]