Several studies have reported that the paraventricular nucleus of the thalamus (PVT) is a sensory relay node in the brain that interacts with fear circuitry. However, little is known about the PVT in relation to safety learning, particularly its interaction with the central nucleus of the amygdala (CeA) in the context of safety expression. Here, […]
BIV-03: Effect of μ-Opioid Receptor Knockout on Fear Conditioning, Extinction, and Morphine-Analgesia
Our understanding of the biological mechanisms underlying fear, trauma, and the development of related disorders like post-traumatic stress disorder (PTSD) are incomplete. Thus, the search for players in the game continues. Among the brain regions identified as exhibiting maladaptive changes/activity in PTSD, the amygdala appears to serve an important role in the acquisition and expression […]
B21: Persistent Effects of Early Life Acute Versus Chronic Footshock Stress on Fear and Anxiety Behaviors in Adulthood.
Anxiety is the most common mental illness in the United States affecting nearly 1 out of 4 Americans and is a major cause of mortality. Posttraumatic stress disorder (PTSD) is the fifth most common psychiatric disorder diagnosis in the United States. Women are 2-3 times more likely to be diagnosed with PTSD and anxiety disorders. […]