The Na+/K+ ATPase is an electrogenic transmembrane ion transport protein that localizes to the plasma membrane in mammals. Its primary function is to maintain the sodium ion and potassium ion electrochemical gradients across the plasma membrane; it does so by utilizing ATP molecules as an energy source. Three major polypeptides make up the Na+/K+ ATPase—the […]
A54: Differences in DNA-Methylation Patterns of the ATP1A4 Gene Between Spermatogenic and Somatic Cell Lines
The Na+/K+-ATPase alpha4 (ATP1A4 gene) ion transporter is an essential protein for sperm cells, as it helps establish an ion gradient used by secondary Na/H exchangers, ultimately directing the intracellular pH of sperm. As this gene has been found significant in spermatogenic cells, previous literature points to differences in DNA methylation patterns of the ATP1A4 […]