Mycoplasma pneumoniae is a pathogenic species of bacteria responsible for up to two million cases of tracheobronchitis and atypical pneumonia every year, and also causes disease of the central nervous system and other anatomical sites. Although M. pneumoniae is unusual among bacteria because of its highly reduced genome and the absence of a cell wall, […]
C01: Molecular analysis of pendulum mutants presenting with defects in heart valve and outflow tract development
Unidirectional blood flow, controlled by valves within the heart, is an essential component for proper and efficient heart function. 30% of patients exhibiting a congenital heart defect present with defects in these valves resulting in decreased heart function. In zebrafish, valve formation occurs at the atrioventricular canal (AVC) and outflow tract (OFT). The signaling pathways […]