The purpose of this experiment was to determine if Chlamydia psittaci is inhibiting caspase activation in HeLa cells through the sequestering of ceramide. This was done by treating cells infected with C. psittaci, as well as uninfected cells, with increasing concentrations of C6-ceramide. A fluorometric multiplex activity assay was used to measure caspase activation.It was […]
A06-P: Prevention of Apoptosis By Chlamydia
Pamela Lewis, a student of Dr. Joseph Carlin’s lab of the Microbiology Department and Director of the Mallory-Wilson Center for Healthcare Education at Miami University, is a microbiology major who is interested in studying Chlamydia trachomatis. She is interested in seeing how HeLa cells infected with C. trachomatis are avoiding apoptosis. Because of this, she […]