B06: Harnessing CRISPR-Cas9 to Reprogram Cell Fate

Destruction of the neural retina in mammals currently leads to irreversible blindness. Unlike humans, newts possess the ability to regenerate a functional neural retina from their retinal pigmented epithelium (RPE), a cell type that lies behind the neural retina. We will develop a method to individually regulate genes by activating and repressing specifically targeted genes. […]

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