{"id":2736,"date":"2020-04-27T19:13:24","date_gmt":"2020-04-27T23:13:24","guid":{"rendered":"https:\/\/sites.miamioh.edu\/undergraduate-research-forum\/?p=2736"},"modified":"2021-03-24T13:00:14","modified_gmt":"2021-03-24T17:00:14","slug":"a14-crown-ether-appended-ortho-phenylenes-with-bound-chiral-guests","status":"publish","type":"post","link":"https:\/\/sites.miamioh.edu\/undergraduate-research-forum\/a14-crown-ether-appended-ortho-phenylenes-with-bound-chiral-guests\/","title":{"rendered":"A14: Crown-ether appended Ortho-phenylenes with bound chiral guests"},"content":{"rendered":"

Many abiotic foldamers are composed of achiral parts but adopt chiral geometries, like helices. In these systems, there is no inherent preference for one handedness of the fold. Ortho-<\/em>phenylenes are a class of aromatic foldamers that fold into helices driven by arene-arene stacking interactions. Although their folding is now reasonably understood, it is not clear what direction the ortho<\/em>-phenylene helix will twist when a chiral guest is bound. Here, we use CD spectroscopy to report that the addition of a chiral ammonium ion molecule to a crown-ether appended ortho<\/em>-phenylene can induce a preferred handedness. We attempt to demonstrate control over this mechanism by choosing chiral groups to favor one orientation.<\/p>\n

Author:<\/strong> Molly Bookout<\/p>\n

Advisors:<\/strong> Dr: Scott C. Hartley. Department of Chemistry and Biochemistry,
\nSumalatha Peddi, Department of Chemistry and Biochemistry<\/p>\n

\"\"<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

Many abiotic foldamers are composed of achiral parts but adopt chiral geometries, like helices. In these systems, there is no inherent preference for one handedness of the fold. Ortho-phenylenes are a class of aromatic foldamers that fold into helices driven by arene-arene stacking interactions. Although their folding is now reasonably understood, it is not clear […]<\/p>\n","protected":false},"author":2899,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_bbp_topic_count":0,"_bbp_reply_count":0,"_bbp_total_topic_count":0,"_bbp_total_reply_count":0,"_bbp_voice_count":0,"_bbp_anonymous_reply_count":0,"_bbp_topic_count_hidden":0,"_bbp_reply_count_hidden":0,"_bbp_forum_subforum_count":0,"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_feature_clip_id":0,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2},"jetpack_post_was_ever_published":false},"categories":[10,27],"tags":[384,89,479],"class_list":["post-2736","post","type-post","status-publish","format-standard","hentry","category-2020-posters","category-chemistry-biochemistry","tag-spectroscopy","tag-stem","tag-synthetic-foldamers"],"aioseo_notices":[],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"","jetpack_sharing_enabled":true,"jetpack_shortlink":"https:\/\/wp.me\/pbRpLx-I8","jetpack_likes_enabled":true,"_links":{"self":[{"href":"https:\/\/sites.miamioh.edu\/undergraduate-research-forum\/wp-json\/wp\/v2\/posts\/2736","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/sites.miamioh.edu\/undergraduate-research-forum\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/sites.miamioh.edu\/undergraduate-research-forum\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/sites.miamioh.edu\/undergraduate-research-forum\/wp-json\/wp\/v2\/users\/2899"}],"replies":[{"embeddable":true,"href":"https:\/\/sites.miamioh.edu\/undergraduate-research-forum\/wp-json\/wp\/v2\/comments?post=2736"}],"version-history":[{"count":0,"href":"https:\/\/sites.miamioh.edu\/undergraduate-research-forum\/wp-json\/wp\/v2\/posts\/2736\/revisions"}],"wp:attachment":[{"href":"https:\/\/sites.miamioh.edu\/undergraduate-research-forum\/wp-json\/wp\/v2\/media?parent=2736"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/sites.miamioh.edu\/undergraduate-research-forum\/wp-json\/wp\/v2\/categories?post=2736"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/sites.miamioh.edu\/undergraduate-research-forum\/wp-json\/wp\/v2\/tags?post=2736"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}